Richard Hibbard is called into the starting line-up to face his former region after Dragons were forced into a late change ahead of the Guinness PRO14 clash with Ospreys (kick-off 7.35pm).
Hooker Hibbard comes in for the injured Ellis Shipp for the Brewery Field fixture.
Rhys Lawrence could also make his first appearance this season after being named among the replacements in Bridgend.
Dragons (v Ospreys): Josh Lewis, Jonah Holmes, Aneurin Owen, Jamie Roberts, Ashton Hewitt, Sam Davies, Gonzalo Bertranou; Brok Harris, Richard Hibbard, Lloyd Fairbrother, Joe Davies, Joe Maksymiw, Ross Moriarty, Harrison Keddie (c), Aaron Wainwright
Replacements: Rhys Lawrence, Josh Reynolds, Aaron Jarvis, Ben Carter, Dan Baker, Rhodri Williams, Jack Dixon, Jordan Williams
